Esmolol

Esmolol- Indications, Dosage, Contraindications, ADRs

Category of Drug Esmolol is Antiarrhythmic Drugs
Mechanism of Action 
Indications Esmolol is used for
1. Supraventricular arrhythmias
2. Atrial fibrillation
3. Flutter
4. Tachycardia and hypertension in the pre-operave period
Well Known
Pharmaceutical Brands
 
Available dosage forms INJECTION
Dose 
Contraindications 1. Asthma
2. Uncontrolled heart failure
3. Prinzmetal’s angina
4. Marked bradycardia
5. Hypotension
6. Sick sinus syndrome
7. Second-or third-degree AV block
8. Cardiogenic shock
9. Metabolic acidosis
10. Severe peripheral arterial
disease
11. Pheochromocytoma
Precautions 1. Avoid abrupt withdrawal especially in ischaemic heart disease
2. First-degree AV block
3. Portal hypertension
4. Diabetes
5. History of obstructive airways disease
6. Myasthenia Gravis
7. Symptoms of hypoglycaemia and thyrotoxicosis may be masked
8. History of hypersensitivity-
may increase sensitivity to allergens and result in more serious hypersensitive response
Adverse Effects 1. Gastrointestinal disturbances
2. Bradycardia
3. Heart failure
4. Hypotension
5. Conduction disorders
6. Peripheral vasoconstriction
7. Bronchospasm
8. Dyspnoea
9. Headache
10. fatigue
11. Sleep disturbances
12. Thrombocytopenia
13. Visual disturbances
14. Exacerbation of psoriasis
15. Alopecia
Pregnancy Category C

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