Category of Drug | Esmolol is Antiarrhythmic Drugs |
Mechanism of Action | |
Indications | Esmolol is used for 1. Supraventricular arrhythmias 2. Atrial fibrillation 3. Flutter 4. Tachycardia and hypertension in the pre-operave period |
Well Known Pharmaceutical Brands | |
Available dosage forms | INJECTION |
Dose | |
Contraindications | 1. Asthma 2. Uncontrolled heart failure 3. Prinzmetal’s angina 4. Marked bradycardia 5. Hypotension 6. Sick sinus syndrome 7. Second-or third-degree AV block 8. Cardiogenic shock 9. Metabolic acidosis 10. Severe peripheral arterial disease 11. Pheochromocytoma |
Precautions | 1. Avoid abrupt withdrawal especially in ischaemic heart disease 2. First-degree AV block 3. Portal hypertension 4. Diabetes 5. History of obstructive airways disease 6. Myasthenia Gravis 7. Symptoms of hypoglycaemia and thyrotoxicosis may be masked 8. History of hypersensitivity- may increase sensitivity to allergens and result in more serious hypersensitive response |
Adverse Effects | 1. Gastrointestinal disturbances 2. Bradycardia 3. Heart failure 4. Hypotension 5. Conduction disorders 6. Peripheral vasoconstriction 7. Bronchospasm 8. Dyspnoea 9. Headache 10. fatigue 11. Sleep disturbances 12. Thrombocytopenia 13. Visual disturbances 14. Exacerbation of psoriasis 15. Alopecia |
Pregnancy Category | C |