Donepezil- Drug Detail Profile

Category of Drug Donepezil is an Anti-Alzheimer and Anti-Parkinsonism Drugs
Mechanism of Action 
Indications Donepezil is used for
1. For the treatment of mild to moderate
Alzheimer’s disease.
Well Known
Pharmaceutical Brands
Available dosage forms TABLETS
Contraindications 1. Hypersensitivity
2. Severe hepatic and renal impairment
3. Pregnancy
4. Lactation
5. not recommended for children
Precautions1. Mechanical intestinal obstruction or peritonitis
2.Recent intestinal or bladder surgery
3. Bronchial asthma or COPD
4. Arrhythmias
5. Bradycardia
6. Recent MI and hypotension
7. Vagotonia
8. Epilepsy
9. Hyperthyroidism
10. Parkinsonism
11. Moderate renal or hepatic impairment or
peptic ulcer
12. Sick sinus syndrome.
Adverse Effects 1. Nausea
2. Vomiting
3. Diarrhoea
4. Fatigue
5. Insomnia
6. Muscle cramps
7. Bradycardia
8. Convulsions
9. Gastrointestinal
10. Haemorrhage
11. Hepatitis
12. Urinary incontinence
13. Influenza
14. pruritus
15. increased liver transaminases.
Pregnancy Category C

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