| Category of Drug | Donepezil is an Anti-Alzheimer and Anti-Parkinsonism Drugs |
| Mechanism of Action | |
| Indications | Donepezil is used for 1. For the treatment of mild to moderate Alzheimer’s disease. |
| Well Known Pharmaceutical Brands | |
| Available dosage forms | TABLETS |
| Dose | |
| Contraindications | 1. Hypersensitivity 2. Severe hepatic and renal impairment 3. Pregnancy 4. Lactation 5. not recommended for children |
| Precautions | 1. Mechanical intestinal obstruction or peritonitis 2.Recent intestinal or bladder surgery 3. Bronchial asthma or COPD 4. Arrhythmias 5. Bradycardia 6. Recent MI and hypotension 7. Vagotonia 8. Epilepsy 9. Hyperthyroidism 10. Parkinsonism 11. Moderate renal or hepatic impairment or peptic ulcer 12. Sick sinus syndrome. |
| Adverse Effects | 1. Nausea 2. Vomiting 3. Diarrhoea 4. Fatigue 5. Insomnia 6. Muscle cramps 7. Bradycardia 8. Convulsions 9. Gastrointestinal 10. Haemorrhage 11. Hepatitis 12. Urinary incontinence 13. Influenza 14. pruritus 15. increased liver transaminases. |
| Pregnancy Category | C |
