Dimercaprol (BAL)- Drug Detail Profile

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Category of Drug	Dimercaprol (BAL) is an Antidotes and Substances Used in Poisoning
Mechanism of Action	The sulfhydryl groups of dimercaprol form complexes with certain heavy metals, thus preventing or reversing the metallic binding of sulfhydryl-containing enzymes. The complex is excreted in the urine.. ¹
Indications	Dimercaprol (BAL) is used for 1. Acute poisoning by antimony 2. Arsenic 3. Bismuth 4. Copper-gold 5. Mercury and possibly thallium 6. Adjunct in lead poisoning
Well Known Pharmaceutical Brands
Molecular details	Weight: 124.225 Chemical Formula- C₃H₈OS₂
Available dosage forms	OILY INJECTION
Dose	As per the physician’s recommendation.
Contraindications	1. Not indicated for 2. Selenium or cadmium poisoning 3. Severe hepatic impairment 4. Hypertension 5. Tellurium poisoning
Precautions	1. Hypertension 2. Renal impairment 3. Any abnormal reaction such as hyperpyrexia should be assessed 4. Pregnancy 5. Lactation 6. Alkalinize urine to pH of 7.5-8.0 using sodium bicarbonate.
Adverse Effects	1. Hypertension 2. Tachycardia 3. Malaise 4. Nausea 5. Vomiting 6. Abdominal pain 7. salivation 8. Lacrimation 9. Sweating 10. Burning sensation in the mouth
Pregnancy Category	C