Dihydroergotamine- Indications, Dosage, Contraindications, ADRs

Category of DrugDihydroergotamine-Antimigraine Drugs-For Treatment of Acute Attack 
Mechanism of Action 
IndicationsDihydroergotamineAntimigraine Drugs-For Treatment of Acute Attack is used for Acute treatment of migraine headaches with
or without aura and acute treatment of cluster headache episodes
Well Known
Pharmaceutical Brands
Available dosage forms1. TABLET
Contraindications1. Peripheral vascular disease
2. Coronary heart disease
3. Obliterative vascular disease and Raynaud’s syndrome
4. Temporal arteries
5. Hepatic impairment
6. Renal impairment
7. Severe or inadequately controlled hypertension
8. Hyperthyroidism
9. Pregnancy 
Precautions1. Risk of peripheral vasospasm
2. Elderly
3. It should not be used for migraine prophylaxis
4. Interactions 
5. Compromised circulation
6. Hypertension
Adverse Effects1. Nausea
2. Vomiting
3. Vertigo
4. Abdominal pain
5. Diarrhoea
6. Muscle cramps
7. Precordial pain
8. Myocardial and intestinal ischaemia
9. High dosage may cause
ergotism with gangrene and confusion
Pregnancy Category X

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