| Category of Drug | Azithromycin is an Anti-Infective drug |
| Mechanism of Action | Azithromycin binds to the 23S rRNA of the bacterial 50S ribosomal subunit. It stops bacterial protein synthesis. |
| Indications | Azithromycin is used for 1. Uncomplicated genital chlamydial infections and trachoma. |
| Well Known Pharmaceutical Brands | AZITHRAL- ALEMBIC AZEE- CIPLA AZITHRAL- ALEMBIC ATM- INDOCO REMEDIES ZADY- MANKIND PHARMA ZATHRIN- FDC LTD |
| Available dosage forms | 1. TABLETS 2. SYRUP 3. INJECTION |
| Dose | 500 mg PO x 1 dose on Day 1, followed by 250 mg PO BID on Days 2-5 |
| Contraindications | 1. Hepatic impairment 2. Hypersensitivity to erythromycin. |
| Precautions | 1. Pregnancy and lactation 2. Renal impairment 3. prolongation of QT interval 4. Interactions 5. exacerbation of symptoms of myasthenia gravis |
| Adverse Effects | 1. Fewer gastrointestinal effects as compared to erythromycin 2. Hepatitis 3. Interstitial nephritis 4. Acute renal failure 5. Paraesthesia 6. Convulsions 7. Mild neutropenia 8. Hepatic failure 9. Taste disturbances |
| Pregnancy Category | B |
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