| Category of Drug | Azathioprine is Immunosuppressives Drug |
| Mechanism of Action | |
| Indications | Azathioprine is used 1. To prevent rejection in transplant recipients 2. Rheumatoid arthritis 3. Inflammatory bowel disease 4. Multiple sclerosis 5. Autoimmune hepatitis 6.Atopic dermatitis (AD) |
| Well Known Pharmaceutical Brands | |
| Available dosage forms | TABLETS |
| Dose | |
| Contraindications | 1. Hypersensitivity to azathioprine and mercaptopurine 2. lactation |
| Precautions | 1. Monitor for toxicity throughout treatment 2. Full blood counts necessary every week 3. Reduce dose in elderly 4. Renal impairment 5. Liver disease 6. Interactions 7. lactation 8. Pregnancy |
| Adverse Effects | 1. Hypersensitivity reaction 2. Rash 3. Hypotension or interstitial nephritis call for immediate withdrawal 4. Haematological toxicity 5. Thrombocytopenia 6. Liver impairment 7. Cholestatic jaundice 8. Hair loss 9. nausea 10. Pancreatitis 11. Pneumonitis |
| Pregnancy Category | D |
