| Category of Drug | Amitriptyline is Antidepressant drug |
| Mechanism of Action | |
| Indications | Amitriptyline is used for 1. Moderate to severe depression 2. Migraine prophylaxis 3. Tension 4. Headache 5. Enuresis |
| Well Known Pharmaceutical Brands | |
| Available dosage forms | 1. TABLETS 2. INJECTION |
| Dose | |
| Contraindications | 1. Recent myocardial infarction 2. Manic phase in bipolar disorders 3. Severe liver disease 4. Children 5. Porphyria 6. Glaucoma 7. Prostatic hypertrophy |
| Precautions | 1. Cardiac disease 2. History of epilepsy 3. lactation 4. Elderly 5. Hepatic impairment 6. Thyroid disease 7. Pheochromocytoma 8. History of mania 9. Psychoses 10. Angle-closure glaucoma 11. History of urinary retention 12. Concurrent electroconvulsive therapy 13. Anaesthesia |
| Adverse Effects | 1. Sedation 2. Dry mouth 3. Blurred vision 4. Constipation 5. Nausea 6. Difficulty in micturition 7. Cardiovascular adverse effects particularly with high dosage 8. Tachycardia 9. Syncope 10. Behavioural disturbances 11. Interference with sexual function 12. Blood sugar changes 13. Abnormal liver function test |
| Pregnancy Category | C |
