| Category of Drug | Isosorbide-5-Mononitrate is Antianginal Drugs |
| Mechanism of Action | |
| Indications | Isosorbide-5-Mononitrate is used for 1. Prophylaxis and treatment of angina 2. Congestive heart failure |
| Well Known Pharmaceutical Brands | |
| Available dosage forms | 1. TABLETS 2. CAPSULES 3. INJECTION |
| Dose | |
| Contraindications | 1. Hypersensitivity to nitrates 2. Hypotensive conditions and hypovolaemia 3. Hypertrophic cardiomyopathy 4. Aortic stenosis 5. Cardiac tamponade 6. Constrictive pericarditis 7. Mitral stenosis 8. Marked anaemia 9. Glaucoma 10. Obstructive cardiomyopathy 11. Raised intracranial pressure. |
| Precautions | 1. Hypothyroidism 2. Malnutrition 3. Hypothermia 4. Head trauma 5. Cerebral haemorrhage 6. Gastrointestinal disease 7. Recent history of myocardial infarction 8. Hypoxaemia or other ventilation and perfusion abnormalities 9. Susceptibility to angle-closure glaucoma 10. Metal-containing transdermal systems should be removed before cardioversion or diathermy 11. Avoid abrupt withdrawal 12. Tolerance 13. Severe hepatic impairment |
| Adverse Effects | 1. Postural hypotension 2. Tachycardia 3. Throbbing headache 4. Dizziness 5. Less commonly nausea 6. Vomiting 7. Heartburn 8. Flushing 9. Temporary hypoxaemia 10. Application site reacons with transdermal patches |
| Pregnancy Category | C |
