Category of Drug | Calcium Disodium Edetate is an Antidotes and Substances Used in Poisoning |
Mechanism of Action | |
Indications | Calcium Disodium Edetate is used for 1. Lead poisoning 2. Lead encephalopathy |
Well Known Pharmaceutical Brands | |
Available dosage forms | AMPOULE |
Dose | |
Contraindications | 1. Anuria 2. Patients with active renal disease or hepatitis 3. Pregnancy |
Precautions | 1. Ensure adequate urine output, pre-existing mild renal disease 2. patients with lead encephalopathy and cerebral edema may experience a lethal increase in intracranial pressure following intravenous infusion, the intramuscular route is preferred for these patients |
Adverse Effects | 1. Renal tubular toxicity which may lead to acute renal failure 2. Fever 3. Chills 4. Lacrimation 5. Increased prothrombin time 6. Pain at the intramuscular injection site 7. Hypotension 8.Cardiac rhythm irregularities 9. Thirst 10. headache 11. fatigue 12. malaise |
Pregnancy Category | B |