Category of Drug | Primaquine is an Anti-Infective drug |
Mechanism of Action | |
Indications | Primaquine is used for 1. Radical cure of P. vivax and P. ovalemalaria 2. elimination of gametocytes of P. Falciparum, malaria prophylaxis. |
Well Known Pharmaceutical Brands | |
Available dosage forms | TABLETS |
Dose | |
Contraindications | 1. Hypersensitivity 2. Granulocytopenia 3. Pregnancy 4. Lactation 5. Children below 1 year |
Precautions | 1. Patients with a history of granulocytosis/ methaemoglobinaemia 2. G-6-PD deficiency 3. Monitor Hb levels 4. Blood counts routinely and withdraws if signs of haemolysis or methaemoglobinaemia occur 5. lactation |
Adverse Effects | 1. Nausea 2. Vomiting 3. Abdominal cramps 4. Haemolytic anaemia in G-6-PD deficient patients 5. Leukopenia 6. Agranulocytosis 7. leukocytosis 8. Methaemoglobinaemia and cardiac arrhythmias. |
Pregnancy Category |