| Category of Drug | Cefotaxime is an Anti-Infective drug |
| Mechanism of Action | Cefotaxime is a parenteral cephalosporin antibiotic, that exerts its bactericidal action through inhibition of bacterial cell wall synthesis. |
| Indications | Cefotaxime is used in Infections due to sensitive Gram-positive and Gram-negative bacteria |
| Well Known Pharmaceutical Brands | TAXIM- ALKEM BIOTAX- ZYDUS CADILA TAXIM- ALKEM BIOTAX- ZYDUS CADILA C-TAX- EMCURE OMNICEF- ARISTO PHARMA MACTAX- MACLEODS PHARMA |
| Available dosage forms | INJECTIONS |
| Dose | Infections Caused by Susceptible Organisms 1. Uncomplicated: 1 g IV or in two divided doses IM 2. Moderate to severe: 1-2 g IV or IM four times a day 3. More serious: 2 g IV; in divided doses 6-8hr |
| Contraindications | 1. Renal disease 2. Hypersensitivity to cephalosporins. |
| Precautions | 1. Impaired kidney or liver disease 2. Colitis 3. History of penicillin allergy 4. Pregnancy |
| Adverse Effects | 1. Local inflammation or pain at the injection site 2. Thrombocytopenia 3. Eosinophilia 4. Leukopenia 5. Pseudomembranous colitis 6. Moniliasis 7. Diarrhoea 8. Candidiasis 9. Decreased urination 10. Seizures 11. Headache 12. Nausea and vomiting 13. Jaundice |
| Pregnancy Category | B |
