Procainamide

Procainamide- Indications, Dosage, Contraindications, ADRs

Category of Drug Procainamide is Antiarrhythmic Drugs
Mechanism of Action 
Indications Procainamide is used for
1. Severe ventricular arrhythmias
2. Especially those resistant to lidocaine or those appearing after myocardial infarction
3. Atrial tachycardia
4. Atrial fibrillation
5. Maintenance of sinus rhythm after cardioversion of atrial
fibrillation
Well Known
Pharmaceutical Brands
 
Available dosage forms 1. TABLET
2. INJECTION
Dose 
Contraindications 1. Asymptomatic ventricular premature contractions
2. Torsades de pointes
3. Systemic lupus erythematosus
4. Heart block
5. Heart failure
6. Hypotension
7. Lactation
8. Children
9. Myasthenia gravis
Precautions 1. Elderly
2. Renal and hepatic impairment
3. Asthma
4. Myasthenia gravis
5. Blood dyscrasias
6. Heart failure
7. Cardiomyopathy
8. Cytopenia
9. Digitalis intoxication
10. Electrolyte imbalance
Adverse Effects 1. Nausea
2. Vomiting
3. Diarrhoea
4. Anorexia
5. Rashes
6. Myocardial depression
7. Heart failure
8. Angioedema
9. Blood disorders include
leukopenia
10. Haemolytic anaemia and
agranulocytosis after prolonged treatment
Pregnancy Category C

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