Category of Drug | Procainamide is Antiarrhythmic Drugs |
Mechanism of Action | |
Indications | Procainamide is used for 1. Severe ventricular arrhythmias 2. Especially those resistant to lidocaine or those appearing after myocardial infarction 3. Atrial tachycardia 4. Atrial fibrillation 5. Maintenance of sinus rhythm after cardioversion of atrial fibrillation |
Well Known Pharmaceutical Brands | |
Available dosage forms | 1. TABLET 2. INJECTION |
Dose | |
Contraindications | 1. Asymptomatic ventricular premature contractions 2. Torsades de pointes 3. Systemic lupus erythematosus 4. Heart block 5. Heart failure 6. Hypotension 7. Lactation 8. Children 9. Myasthenia gravis |
Precautions | 1. Elderly 2. Renal and hepatic impairment 3. Asthma 4. Myasthenia gravis 5. Blood dyscrasias 6. Heart failure 7. Cardiomyopathy 8. Cytopenia 9. Digitalis intoxication 10. Electrolyte imbalance |
Adverse Effects | 1. Nausea 2. Vomiting 3. Diarrhoea 4. Anorexia 5. Rashes 6. Myocardial depression 7. Heart failure 8. Angioedema 9. Blood disorders include leukopenia 10. Haemolytic anaemia and agranulocytosis after prolonged treatment |
Pregnancy Category | C |