| Category of Drug | Busulphan is Immunosuppressives Drug |
| Mechanism of Action | |
| Indications | Busulphan is used for 1. Chronic granulocytic leukaemia 2. Chronic myelogenous leukaemia 3. Polycythaemia vera 4. Myelofibrosis 5. Thrombocythaemia |
| Well Known Pharmaceutical Brands | |
| Available dosage forms | TABLET |
| Dose | |
| Contraindications | 1. Pregnancy 2. Bone marrow suppression 3. Chronic lymphocytic leukaemia 4. Lactation |
| Precautions | 1. Monitor cardiac function 2. Pregnancy 3. lactation previous radiation therapy 4. Avoid in porphyria 5. Hepatic impairment 6. Interactions |
| Adverse Effects | 1. Hepatotoxicity 2. Cardiac tamponade at high doses in thalassaemic patients 3. Pneumonia 4. Skin hyperpigmentation 5. Hyperuricemia 6. Pulmonary fibrosis |
| Pregnancy Category | D |
