Mitomycin

Mitomycin- Indications, Dosage, Contraindications, ADRs

Category of Drug Mitomycin is Immunosuppressives Drug
Mechanism of Action 
Indications Mitomycin is used for
1. Adenocarcinoma
2. Lymphosarcoma and
seminoma
3. Superficial bladder cancer
Well Known
Pharmaceutical Brands
 
Available dosage forms INJECTIONS
Dose 
Contraindications 1. Pregnancy
2. Bone marrow depression
3. Severe anaemia
4. Thrombocytopenia
5. lactation
Precautions It causes delayed bone-marrow toxicity and therefore it is usually administered at 6-weekly
intervals
Adverse Effects 1. Prolonged use may result in permanent bone-marrow damage
2. It may also cause lung fibrosis and renal damage
3. Dyspnea
Pregnancy Category D

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