| Category of Drug | Flumazenil-Antidote is Antidotes and Substances Used in Poisoning. |
| Mechanism of Action | |
| Indications | Flumazenil-Antidote is used for 1. The antidote for benzodiazepine overdose 2. Reversal of sedative effects produced by benzodiazepines administered during general anaesthesia or diagnostic or therapeutic procedures |
| Well Known Pharmaceutical Brands | |
| Available dosage forms | INJECTION |
| Dose | |
| Contraindications | 1. Epilepsy 2. Neuromuscular blockade 3. Hypersensitivity to benzodiazepines 4. Patients of suspected tricyclic antidepressant overdose 5. Raised intracranial pressure. |
| Precautions | 1. History of seizures 2. Panic attack 3. Alcohol drug dependence 4. Bleeding disorder 5. Liver disease 6. Head injury 7. Respiratory depression 8. Pregnancy |
| Adverse Effects | 1. Convulsions 2. Fatigue 3. Injection site pains 4. Increased sweating 5. Facial erythema 6. Raised intracranial pressure 7. Agitation 8. Dizziness 9. Abnormal vision 10. may cause complete heart block 11. Flushing 12. Transient increase in blood pressure and heart rate |
| Pregnancy Category | C |
